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Clinical Trials/NL-OMON28957
NL-OMON28957
Recruiting
Not Applicable

A randomized controlled trial to investigate the efficacy of a multispecies probiotic supplement (Ecologic® BARRIER) on symptoms of fatigue in subjects with Inflammatory Bowel Disease

Winclove B.V.0 sites230 target enrollmentTBD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Not specified
Sponsor
Winclove B.V.
Enrollment
230
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
last year
Study Type
Interventional

Investigators

Sponsor
Winclove B.V.

Eligibility Criteria

Inclusion Criteria

  • Subjects between the ages of 18 and 65 years old.
  • Subjects diagnosed with Crohn’s disease or Ulcerative Colitis.
  • Subjects with a score of 4 or higher on the Chalder Fatigue Questionnaire.

Exclusion Criteria

  • Subjects with active inflammation. Disease has to be in remission defined as CRP \= 10 mg/l, leucocytes between 4\.0\-10\.0 10E9/l and calprotectin levels of \= 100 µg/g.
  • Subjects with abnormal laboratory values, including but not limited to hemoglobin, vitamin B12 and folic acid levels. These need to be corrected and retested before entering the study.
  • Subjects who used probiotics (including probiotic\-containing products such as Yakult, Actimel, etc), antibiotics or Non\-Steroidal Anti\- Inflammatory Drugs (NSAIDs) in the 4 weeks prior to the screening visit, or are planning to do so during the study.
  • Subjects with local manifestation of IBD for which surgery might be indicated or which could confound the evaluation of efficacy.
  • Subjects who have had placement of a stoma or pouch.
  • Subjects who are pregnant, lactating or planning pregnancy while enrolled in the study.
  • Subjects who are unsuitable for inclusion in the study in the opinion of the investigator for any reason that may compromise the subject’s safety or confound data interpretation.

Outcomes

Primary Outcomes

Not specified

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