NCT01073202已完成不适用
Effects of Ursodeoxycholic Acid on Graft Recovery Early After Adult Liver Transplantation
Shanghai Jiao Tong University School of Medicine1 个研究点 分布在 1 个国家目标入组 112 人开始时间: 2005年5月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 112
- 试验地点
- 1
- 主要终点
- Serum liver tests
研究概览
简要总结
This study is designed to investigate the possible beneficial effects of UDCA on liver graft recovery early after adult liver transplantation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All liver transplant patients in our center between May 2005 and April 2008 were potentially eligible for enrollment
排除标准
- •Age less than 18 years
- •Treatment with UDCA within one month before operation
- •Inability to provide written informed consent prior to study entry
- •Non-liver organ(s) failure prior to entry
研究组 & 干预措施
ursodeoxycholic acid
Active Comparator
干预措施: ursodeoxycholic acid (Drug)
identical-appearing placebo
Placebo Comparator
干预措施: identical-appearing placebo (Drug)
结局指标
主要结局
Serum liver tests
时间窗: within the first 4 weeks after liver transplantation
Serum liver tests include serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma glutamyl transpeptidase (GGT), alkaline phosphatase (ALP) and total bilirubin (TB)
次要结局
- Postoperative complications(within the first 4 weeks after liver transplantation)
研究者
研究点 (1)
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