Singapore Cardiac Longitudinal Outcomes Database
- Conditions
- Congestive Heart FailureAtrial FibrillationCoronary Artery Disease
- Interventions
- Other: Data Collection
- Registration Number
- NCT03760705
- Lead Sponsor
- National Heart Centre Singapore
- Brief Summary
The research project aims to perform data extraction, integration and analysis across multiple clinical, administrative, financial and pharmacy databases in the participating institutions. The key data components will include clinical cardiovascular specific data, procedural data, financial and administrative data (e.g. cost of medications and supplies, length of stay, diagnosis codes etc.), short-to-long term clinical outcomes (including hospital re-admissions, cardiovascular events, death), and quality-of-care indices (e.g. compliance to guideline-recommended therapy and medications). The research project will involve all patients proven and/or suspected with coronary artery disease (CAD), congestive heart failure (CHF) and atrial fibrillation (AF) admitted to National Heart Centre Singapore (NHCS) and NUH.
- Detailed Description
The research project is initiated by NHCS and its participating institutions include Ministry of Health (MOH), as well as National University Hospital (Singapore) Pte Ltd (NUH), Changi General Hospital (CGH), Khoo Teck Puat Hospital (KTPH), Singapore General Hospital (SGH), Tan Tock Seng Hospital (TTSH), Ng Teng Fong General Hospital (NTFGH) , SingHealth Polyclinics, National Healthcare Group Polyclinics (NHGP), Sengkang Hospital (SKH), National University Polyclinics (NUP), and Alexandra Hospital (AH).
The research project will leverage on the Health Data Grid (HDG) pilot project, now known as Business Research Analytics Insights Network (BRAIN). BRAIN will be a virtual repository that will enable access to anonymised and merged data from disparate databases at multiple institutions. The structures of BRAIN will preserve patients' privacy and confidentiality, ensure IT security and allow access only by authorised persons. The BRAIN pilot project will be co-funded by MOH and the Infocommunication Media Development Authority of Singapore (IMDA). To avoid doubt, after the BRAIN pilot project, a separate approval from the appropriate stakeholders will have to be sought for further funding of the operating costs of the BRAIN, regardless of whether the value of the BRAIN has been demonstrated during the BRAIN pilot project. There is no direct cost involved in the research project.
For the research project, MOH will contribute administrative data from the Registry of Births and Deaths, Casemix \& Subvention, the Mediclaim, and Omnibus databases, and the other participating institutions will contribute the data from the National Electronic Health Records (NEHR), Electronic Health Intelligence System (eHIntS) and Enterprise Data Warehouse (EDW) to BRAIN. Only anonymised data from BRAIN will be utilised for the research project.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 7205000
- all patients who present to a healthcare institution with either CAD or suspected CAD (including chest pain); CHF or suspected CHF; AF or suspected AF
- non-Singaporeans
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Atrial Fibrillation Data Collection 1. Clinical data collected by Singapore Cardiac Data Bank (SCDB) 2. Clinical, administrative, pharmacy, financial data collected by each participating hospital 3. Administrative data collected by the Ministry of Health Heart Failure Data Collection 1. Clinical data collected by Singapore Cardiac Data Bank (SCDB) 2. Clinical, administrative, pharmacy, financial data collected by each participating hospital 3. Administrative data collected by the Ministry of Health Coronary Artery Disease Data Collection 1. Clinical data collected by Singapore Cardiac Data Bank (SCDB) 2. Clinical, administrative, pharmacy, financial data collected by each participating hospital 3. Administrative data collected by the Ministry of Health
- Primary Outcome Measures
Name Time Method The primary outcome measure will be to assess the total number of patients who passed away due to any cause at the 3-year time point 3 year Mortality
The primary outcome measure will be to assess the total number of patients who passed away due to any cause at the 2-year time point 2 year Mortality
The primary outcome measure will be to assess the total number of patients who passed away due to any cause at the 1-year time point 1 year Mortality
- Secondary Outcome Measures
Name Time Method The secondary outcome measure will be to assess the total number of patients who had MACE due to any cause at the 3-year time point 3 year MI, Stroke, CHF
The secondary outcome measure will be to assess the total number of patients who had major adverse cardiac event (MACE) due to any cause at the 1-year time point 1 year Myocardial Infarction (MI), Stroke, CHF
The secondary outcome measure will be to assess the total number of patients who had MACE due to any cause at the 2-year time point 2 year MI, Stroke, CHF
Trial Locations
- Locations (13)
SingHealth Polyclinics
🇸🇬Singapore, Singapore
National Heart Centre Singapore
🇸🇬Singapore, Singapore
Tan Tock Seng Hospital Pte Ltd
🇸🇬Singapore, Singapore
Khoo Teck Puat Hospital
🇸🇬Singapore, Singapore
Ng Teng Fong General Hospital
🇸🇬Singapore, Singapore
National University Hospital (Singapore) Pte Ltd
🇸🇬Singapore, Singapore
National Healthcare Group Polyclinics
🇸🇬Singapore, Singapore
National University Polyclinics
🇸🇬Singapore, Singapore
Changi General Hospital
🇸🇬Singapore, Singapore
Sengkang Hospital
🇸🇬Singapore, Singapore
Alexandra Hospital
🇸🇬Singapore, Singapore
Singapore General Hospital
🇸🇬Singapore, Singapore
Ministry of Health
🇸🇬Singapore, Singapore