跳至主要内容
临床试验/NCT00655070
NCT00655070终止早期 1 期

Evaluation of the Effect of T3US on Myocardial Blow Flow in the Hibernating

University of California, San Francisco2 个研究点 分布在 1 个国家目标入组 9 人开始时间: 2008年4月1日最近更新:
适应症

试验速览

阶段
早期 1 期
状态
终止
入组人数
9
试验地点
2
主要终点
Change in myocardial blood flow from baseline to post ultrasound treatment

研究概览

简要总结

The purpose of this study is to evaluate whether the use application of low frequency ultrasound, administered by the Timi3 ultrasound device, increases myocardial blood flow to the heart, in subjects with reduced myocardial blood flow at rest (hibernating myocardium). The primary endpoint of the trial is to assess the increase in myocardial blood flow from baseline to post Timi3 Ultrasound treatment in a hypoperfused region of myocardium. Positron emission tomography (PET) imaging will be used to noninvasively evaluate cardiac blood flow. The hypothesis is that ultrasound increases blood flow in hibernating myocardium.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • >/= 18 years
  • Must have reversible resting ischemia, resting non-reversible blood flow defect, or stress-induced ischemia.
  • Females with childbearing potential must not be pregnant at the time of the study
  • Must provide written informed consent

排除标准

  • Unable or unwilling to cooperate with study procedures
  • Currently enrolled in another clinical study for which the follow-up period is not complete

结局指标

主要结局

Change in myocardial blood flow from baseline to post ultrasound treatment

时间窗: immediate post treatment

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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