Gonadal Toxicity in Women With Hodgkin Lymphoma
- Conditions
- Hodgkin Lymphoma
- Registration Number
- NCT01008735
- Lead Sponsor
- Gruppo Italiano Studio Linfomi
- Brief Summary
The Gruppo Italiano Studio Linfomi has been collecting data on patients with Hodgkin Lymphoma (HL) since 1988. This archive represents a homogeneous series of consecutive patients with HL. The very long follow up and the availability of clinical and treatment data make it feasible to perform a study on the gonadal toxicity related to treatment for HL.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 150
Inclusion Criteria
- Female patients in complete remission after chemotherapy for Hodgkin lymphoma
- Age ≥ 18 e < 40 years
- Previous regular menstrual cycle
- No previous or concomitant gynecological diseases affecting reproducing function
- No other chemo-radiotherapy for other neoplasm
- Written informed consent
Exclusion Criteria
- none
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method incidence of gonadal toxicity in terms of irreversible amenorrhea and infertility, in women of reproductive age with Hodgkin lymphoma treated with chemotherapy. from end of treatment until date of last contact/visit
- Secondary Outcome Measures
Name Time Method role of a prophylactic treatment with oral contraceptives and GnRH analogs in preventing gonadal damage from end of treatment until date of last contact/visit
Trial Locations
- Locations (1)
Gruppo Italiano Studio Linfomi
🇮🇹Modena, Italy