Effect of Sulforaphane on prostate CAncer PrEvention (ESCAPE)

Not Applicable

Completed

• Conditions: Topic: National Cancer Research Network; Malignant neoplasm of prostate; Subtopic: Prostate Cancer; Disease: Prostate; Cancer

• Registration Number: ISRCTN40496794
• Lead Sponsor: Quadram Institute Bioscience

Brief Summary

2019 results in: https://www.ncbi.nlm.nih.gov/pubmed/30982861 (added 13/08/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-10-11
• Study Completion: 2017-10-31
• Last Update Posted: 5 July 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 49

Inclusion Criteria

1. Males
2. Diagnosed with low and intermediate prostate cancer on active surveillance
3. Aged 18-80 years
4. Body mass index (BMI) between 19.5 and 35 kg/m2
5. Smokers and non-smokers

Exclusion Criteria

1. Those undergoing chemopreventive therapy
2. Those regularly taking 5a-reductase inhibitors or testosterone replacement medicines
3. Those on warfarin treatment
4. Those diagnosed with diabetes
5. Those diagnosed with or suspected to be high-risk for HIV and/or hepatitis
6. Those allergic to any of the ingredients of the broccoli soups
7. Those taking dietary supplements or herbal remedies which may affect the study outcome unless the volunteer is willing to discontinue taking them for 1 month prior to starting study. Please note that some supplements may not affect the study and this will be assessed on an individual basis
8. Parallel participation in another research project which involves dietary intervention
9. Any person related to or living with any member of the study team

Study & Design

• Study Type: Interventional
• Study Design: Not specified