Investigation of the auditory pathway in asymmetric hearing impaired patients with fMRI and comparison to [18F]FDG-PET images

HNO-Uniklinik Freiburg0 sites26 target enrollmentJune 27, 2019

Overview

No summary available.

Registry

who.int

Start Date

June 27, 2019

End Date

January 1, 2021

Last Updated

last year

Study Type

Interventional

Sex

All

Sponsor

HNO-Uniklinik Freiburg

•AHL patients
•\- Hearing ability of the poorer ear: severe hearing loss up to hearing loss bordering on deafness.
•\- Hearing ability of the better ear: air conduction hearing threshold in the range up to and including 4 kHz of \> 30 dB HL and \= 60 dB HL
•\- Preferred AHL patients who have received an \[18F]FDG PET image due to a clinical indication with good image quality.
•NH subjects
•\- Hearing in both ears: Air conduction hearing threshold in the 125\-8000 Hz range of \= 20 dB HL
•\- Speech intelligibility threshold in Oldenburg sentences test for S0N0 (fixed noise level of 65dB SPL and a start speech level of 65dB SPL)
•\- Monaural left: \= \-6 dB
•\- Monaural right: \= \-6 dB
•\- Binaural: \= \-6 dB

•\- Age \< 18 years and \> 65 years
•\- Left\-handers (Edinburgh Handsiness Inventory: Laterality Quotient\< 60\)
•\- relevant neurological or psychiatric concomitant disease (e.g. cognitive impairment, epilepsy, cerebrovascular disease, brain tumor, depression, etc.)
•\- Diseases that may be expected to lead to inadequate compliance with fMRI (e.g. back pain, severe claustrophobia, incontinence, metal implants, etc.)
•\- Pregnancy