Study on the Effect and Mechanism of Thi Chi for Motor Dysfunction in Different Stages of Stroke: a Multicentre Randomized Controlled Trial.

Phase 1

• Conditions: Stroke

• Registration Number: ITMCTR2000003359
• Lead Sponsor: The Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Stroke was diagnosed by cranial CT or MRI according to the diagnosis of all kinds of major cerebrovascular diseases in China (2019), revised by the guidance consensus expert committee of neurology branch of the Chinese medical association and cerebrovascular group of neurology branch of the Chinese medical association.
(1) first onset, age 45~65 years old, unilateral limb paralysis;
(2) stand for more than 5 minutes and walk for more than 6 meters without any assistance;
(3) clinical dementia rating scale (CDR) score <= 0.5;
(4) spasmodic period into the onset time of 14 days to two months, upper limb Brunnstrom IV, lower limb Brunnstrom III~ IV, spasm of modified Ashworth rating scale 1 ~ 2 levels of patients;
(5) convalescent period into the onset time of 14 days to six months, Brunnstrom V, spasm of modified Ashworth rating scale 0 level patients;
(6) voluntarily participate in the study and sign the informed consent.

Exclusion Criteria

(1) patients with acute cerebral thrombosis or unilateral neglect;
(2) patients with previous history of dementia or mental illness, visual and hearing impairment, or severe diseases of heart, lung, liver, kidney, various malignant tumors and other contraindications;
(3) those who have experience in practicing Tai Chi;
(4) motor dysfunction not caused by stroke;
(5) those who cannot detect Nuclear Magnetic and Surface EMG Signals due to metal device implantation or other reasons;
(6) failing to complete the training or failing to cooperate due to other functional disorders;
(7) participants who are participating in other studies that influence the results of this study.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Modified Ashworth Scale;Fugl-Meyer Motor Function Assessment (FMA) Score;

Secondary Outcome Measures

Name	Time	Method
Six-minute Walking Test (6MWT);Surface EMG signal;Berg Balance Scale;Nuclear Magnetic Resonance Index;SF-36 Quality of Life Scale;Modified Barthel Index (MBI);