Improving the effectiveness of misoprostol cervical ripening with laminaria
Phase 2
- Conditions
- Abortion.termination of pregnancy: legal therapeutic therapeutic abortion
- Registration Number
- IRCT2014070711020N4
- Lead Sponsor
- Vice Chancellor for research of Tehran University of Medical Sciences , Deputy of Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 70
Inclusion Criteria
18 to 35 years ;gestational age less than 14 weeks;closed cervix;ultrasound consecutive Blighted Ovoum or Missed Abortion or the termination of pregnancy to order a forensic document.
Exclusion criteria: medical conditions such as diabetes or high blood pressure or heart disease; surgery on the cervical area of ??the convention; women who take certain medications or an underlying allergy;Women who have vaginal bleeding at presentation ; women with a BMI of less than 20 or more than 25 ; more than 2 previous cesarean section; uterine anomalies .
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 400µg sublingual misoprostol for cervical ripening. Timepoint: Every 4 hours. Method of measurement: =Hegar7.;Cervical ripening with:cervical laminaria plus 200µg sublingual misoprostol. Timepoint: Every 4 hours. Method of measurement: =Hegar7.
- Secondary Outcome Measures
Name Time Method Symptoms of allergy to laminaria. Timepoint: every tow hours up to cervix prparation. Method of measurement: based on fever and Itching existance.;Fever. Timepoint: every 2 hours up to preparation ofcervix. Method of measurement: Medical thermometer.