Real Dairy Diets for Human Health

Active, not recruiting

• Conditions: Post-meal inflammatory and metabolic responses to high and low fat meals.; Diet and Nutrition - Obesity; Inflammatory and Immune System - Normal development and function of the immune system; Cardiovascular - Normal development and function of the cardiovascular system

• Registration Number: ACTRN12610000562077
• Lead Sponsor: Deakin University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-07-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: Male
• Target Recruitment: 40

Inclusion Criteria

Lean subjects are included based on a waist circumference less than 94cm.

Metabolic Syndrome subjects are included based on having a waist circumference greater than 94cm, plus two of the following; fasting serum triglycerides greater or equal to 1.7mmol/l, fasting plasma glucose greater or equal to 5.6mmol/l; serum high density lipoprotein cholesterol (HDL) less than 1.03mg/l; systolic blood pressure either greater than or equal to systolic 130mmHG.

Exclusion Criteria

The presence of confirmed diabetes or heart disease.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Immune responses to a meal: - inflammatory signals and gene expression in immune cells found in the blood[Blood is taken before the meal and at hourly intervals after the meal for 6 hours.]

Secondary Outcome Measures

Name	Time	Method
Adipose and muscle responses to a meal; - Adipose and muscle gene and protein signaling responses to the meal will be measured.[Adipose and skeletal muscle will be taken using needle biopsy before the meal and again 2 and 4 hours after each meal.]