Evaluation of the efficacy of transgingival photodynamic therapy (Tg-PDT) using blue light LED (430-490nm) as an adjunct to subgingival mechanical instrumentation - A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- The efficacy of transgingival photodynamic therapy (Tg-PDT) using blue light LED (430-490nm) as an adjunct to subgingival mechanical instrumentation will be evaluated based on clinical and immunological parameters.
研究概览
简要总结
Low power LASERS + photosensitizer dyes are being used to treat periodontitis, but high cost, potential to cause eye damage, thermogenesis, production of plume are the main disadvantages of LASERS. LED can emit various wavelengths of light. Lower directivity of LED light is suitable for the application over large surfaces. Moreover, every dental clinic is equipped with a blue LED light curing unit (430-490nm) for curing composite restorations. Endogenous porphyrins produced by the periodontopathogenic bacteria are effective chromophores for the blue wavelengths of light thus precluding the necessity of using exogenous photosensitizer.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Generalized Stage II, Grade B periodontitis 2)Probing Pocket Depth- 4-5 mm 3)Individuals with thin periodontal phenotype (gingival thickness ≤ 2mm) 4)Subjects having at least 20 remaining teeth 5) No systemic disease.
排除标准
- •Subjects who have undergone periodontal treatment within last 6 months 2) Subjects with history of systemic antibiotic administration within the last 6 months.
- •Smokers 4) Pregnancy or Lactation 5) Chronic high dose steroid use.
结局指标
主要结局
The efficacy of transgingival photodynamic therapy (Tg-PDT) using blue light LED (430-490nm) as an adjunct to subgingival mechanical instrumentation will be evaluated based on clinical and immunological parameters.
时间窗: At baselinse and at 6th week
次要结局
- To evaluate and compare the clinical and immunological effects of scaling and root planing along with transgingival photodynamic therapy (SRP + Tg–PDT) using blue LED light (430-490nm) and scaling and root planing (SRP) alone in the treatment of generalized periodontitis.(baseline and 6 weeks)
研究者
Dr Arunangshu Deb
Bharati Vidyapeeth Dental College and Hospital