NL-OMON56740
Recruiting
Not Applicable
Sequential diagnostics of pulmonary fungal infections - SIGNALS
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- invasive fungal infection
- Sponsor
- Radboud Universitair Medisch Centrum
- Enrollment
- 120
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age 18 yrs and older • Inclusion within 1 day before start of cytoreductive
- •treatment or remission induction chemotherapy for acute myeloid leukemia (AML)
- •or myelodysplastic syndrome (MDS) OR for myeloablative conditioning of
- •allogeneic stem cell transplantation (HSCT) including FLAMSA conditioning •
- •Expected absolute neutrophil count of \<0\.5 x109 for at least 10 days • No
- •previous or current history of proven or probable IMD • No current diagnosis of
- •pneumonia • No current respiratory distress or ventilation support ( low flow
- •oxygen is permitted ie by nasal canula) • Patients must be able to be
- •transferred to the radiology department for scanning • Female subjects with
- •childbearing potential must have a negative serum (or urine) pregnancy test
Exclusion Criteria
- •Pregnant female subjects
- •Current or previous history of primary or metastatic lung malignancy
- •Treatment for pulmonary fungal infection in preceding 3 months
- •Inflammatory bowel disease or any inflammatory bowel condition
Outcomes
Primary Outcomes
Not specified
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