Observational prospective study to evaluate clinical significance of endothelial vasomotor function in the culprit coronary artery in patients with acute myocardial infarctio
- Conditions
- Acute myocardial infarction
- Registration Number
- JPRN-UMIN000018434
- Lead Sponsor
- niversity of Yamanashi, Department of Internal Medicine II
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 200
Not provided
The study patients met any of the following exclusion criteria were excluded: 1) organic stenosis > 30% in the LAD at 2 weeks and 6 months after AMI; 2) percutaneous coronary intervention at multiple segments of the LAD; 3) in-stent and peri-stent restenosis (> 30% diameter stenosis) at the 6 month study after AMI; 4) previous percutaneous coronary intervention in the LAD before AMI; 5) previous coronary artery bypass surgery before AMI; 6) cardiovascular events during 6 months after AMI; 7) congestive heart failure; 8) persistent atrial fibrillation or a paced rhythm; 9) presence of collaterals to the LAD with Rentrop grade > 2; 10) valvular heart diseases, secondary hypertension, stroke, renal dysfunction (serum creatinine concentration > 2.0 mg/dl) or other serious diseases, 11) Left main trunk disease.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The following outcomes at 6 months and during 5.5 years after AMI will be evaluated. 1. Left ventricular function, 2. Targeted vessel revascularization in the culprit coronary artery,
- Secondary Outcome Measures
Name Time Method