Comparison of different methods of tranexamic acid administration on post operative blood loss

Phase 3

Recruiting

• Conditions: Amount of bleeding following total knee arthroplasty.; Presence of unspecified artificial knee joint; Z96.659

• Registration Number: IRCT20160105025871N2
• Lead Sponsor: Kerman University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 November 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Patients who scheduled to undergo a unilateral total knee arthroplasty

Exclusion Criteria

Cardiovascular diseases
Cerebrovascular diseases
Bleeding disorders
Known allergy to tranexamic acid
Receiving the anti-coagulant drugs
History of thromboembolic disease

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The amount of hemoglobin. Timepoint: Preoperatively, 24 hours postoperatively and in the morning discharge day. Method of measurement: Complete Blood Count (CBC) test.;Post-operative drained blood volume. Timepoint: 48 hours after the operation. Method of measurement: Hemovac drain.

Secondary Outcome Measures

Name	Time	Method
Surgical site infection. Timepoint: 48 hours postoperatively. Method of measurement: clinical examination.