Evaluation of the Concentrations of Inflammatory, Protein and Oxidative Biomarkers of Parkinson's Disease After Photobiomodulation From Sublingual Laser Application - Clinical, Randomized and Blind Test
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Parkinson Disease
- Sponsor
- University of Nove de Julho
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- 10-meter walk test
- Last Updated
- 5 years ago
Overview
Brief Summary
This study evaluates the use of photobiomodulation in the treatment of patients with Parkinson's disease. Half of participants will receive treatment with low level laser therapy and exercises in combination, while the other half will receive a placebo laser combined with exercises.
Investigators
Daysi Tobelem
Master degree
University of Nove de Julho
Eligibility Criteria
Inclusion Criteria
- •patients with Parkinson's disease diagnosed with the criteria of the UK Parkinsons' Disease Society Brain Bank Clinical Diagnostic Criteria
- •In the stages I to III of the disease according to Hoehn \& Yahr's Parkinson's disease staging scale - modified;
- •Individuals of both sexes,
- •with more than 50 years
- •who sign the informed consent form
Exclusion Criteria
- •patients who present some adverse event during the development of the study,
- •Who have another associated neurodegenerative disease,
- •Have blood dyscrasia, HIV, heart failure, hepatic or renal insufficiency, infections, neoplasias, respiratory disorders, hypophysis and hypothalamus problems.
- •Who fail to understand or perform procedures correctly because of physical and mental limitations.
Outcomes
Primary Outcomes
10-meter walk test
Time Frame: 1 day
This evaluation will be carried out from the application of the tem meter walk test. The test will be performed in a straight hall, with a line 14 meters long. The first 2 meters marked, will be provided so that the patient reaches the usual walking speed, and the last 2 meters will be provided for the patient to decelerate and stop. At the start of the test, patients will receive walking guidance at a comfortable pace.