Fast detoxification of opioid addiction in patients suffering from opioids induced hyperalgesi (OIH) - Detoxification of opioids during sedation with Rapid Opioid Detoxificatio
- Conditions
- Patient suffering from opioid induced hyperalgesi (OIH).
- Registration Number
- EUCTR2009-015866-71-SE
- Lead Sponsor
- Karolinska University Hospital Huddinge
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- men and women between 18-70 years old
- with a opioid induced hyperalgesi
- have tried conventional detoxification without success
- no allergy to IMP
- have to quit smoking approxiamatly 3 months before enetring trial
- women have to use anticonception during study and after three months of study period ending
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
- seroius disease or other clinical symtoms indication underlying disorder according to American Society of Anasetsia classification system.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: To evaluate patients the feasability of a rapid opioid detoxification (ROD);Secondary Objective: To evaluate patients experience in Quality of life and pain after rapid opioid detoxification (ROD);Primary end point(s): EQ-5D scale, VAS scale, Sickness Impact profile, HospitalAnxiety and Depression Scale.
- Secondary Outcome Measures
Name Time Method