NCT04149028已完成不适用
Platelet Rich Plasma Injection Into Ovary of Patients With Premature Ovarian Insufficiency
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Resumption of ovarian folliclugenesis
研究概览
简要总结
All encountered cases with POI will be assessed and examined then investigated. Eligible cases will be included in the study
详细描述
Patients will be subjected to injection of autologous PRP inside the ovary about 0.5-1 mml by laparoscopy
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Premature ovarian insufficiency diagnosed by:
- •FSH> 40 Amenorrhea Menopuasal symptoms Infertility
排除标准
- •Refusal to participate Secondary POI due chemotherapy, surgery, or radiotherapy Previous treatment with PRP
研究组 & 干预措施
PRP injection
Experimental
injection of PRP inside ovary by the assistance of laparoscopy
干预措施: PRP injection inside the ovary by laparoscoy. The injection volume is 2 ml (Procedure)
结局指标
主要结局
Resumption of ovarian folliclugenesis
时间窗: 3-6 months
Assessment of the presence of oocytes by trans vaginal ultrasound on day 3
Resumption of ovarian hormonal function
时间窗: 3-6 months
Measurement of Estradiol level on Day 3 of cycle
次要结局
- Resumption of menstruation(3-6 months)
- Fertility potential(3-6 months)
研究者
Ayman S Dawood, MD
Lecturer of Obstetrics and gynecology
Tanta University
研究点 (1)
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