Platelet Rich Plasma Injection Into Ovary of Patients With Premature Ovarian Insufficiency
Not Applicable
Completed
- Conditions
- Premature Ovarian Failure
- Interventions
- Procedure: PRP injection inside the ovary by laparoscoy. The injection volume is 2 ml
- Registration Number
- NCT04149028
- Lead Sponsor
- Tanta University
- Brief Summary
All encountered cases with POI will be assessed and examined then investigated. Eligible cases will be included in the study
- Detailed Description
Patients will be subjected to injection of autologous PRP inside the ovary about 0.5-1 mml by laparoscopy
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 16
Inclusion Criteria
- Premature ovarian insufficiency diagnosed by:
- FSH> 40 Amenorrhea Menopuasal symptoms Infertility
Exclusion Criteria
- Refusal to participate Secondary POI due chemotherapy, surgery, or radiotherapy Previous treatment with PRP
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description PRP injection PRP injection inside the ovary by laparoscoy. The injection volume is 2 ml injection of PRP inside ovary by the assistance of laparoscopy
- Primary Outcome Measures
Name Time Method Resumption of ovarian folliclugenesis 3-6 months Assessment of the presence of oocytes by trans vaginal ultrasound on day 3
Resumption of ovarian hormonal function 3-6 months Measurement of Estradiol level on Day 3 of cycle
- Secondary Outcome Measures
Name Time Method Resumption of menstruation 3-6 months Occurrence of Menstruation after secondary amenrorrhea by questionnaire
Fertility potential 3-6 months Potential to get pregnant after ICSI procedure
Trial Locations
- Locations (1)
Adel Elgergawy
🇪🇬Tanta, Egypt