The Effects of Ultrasound-guided Serratus Plane Block During Video-assisted Thoracoscopic Lobectomy

Not Applicable

• Conditions: Anesthesia, Conduction; Pain Management
• Interventions: Procedure: General anesthesia only; Procedure: Serratus plane block

• Registration Number: NCT03718377
• Lead Sponsor: Kyungpook National University Hospital

Brief Summary

This study evaluates the effects of serratus plane block on intraoperative opioid consumption, emergence time and hemodynamic stability in patients undergoing video-assisted thoracic surgery.

Detailed Description

Thoracotomy is known as one of the most painful surgery. Thus, there is a development to reduce surgical stress in terms of operation technique, which is video-assisted thoracoscopic surgery. Although it has reduced postoperative pain and complications compared with thoracotomy, VATS is still quite painful operation.

Serratus plane block is a novel technique which provide analgesic effect for lateral chest wall by blocking lateral branch of intercostal nerve. It has been reported to be used for pain management including rib fracture, herpes zoster, and postoperative pain. It has become a popular analgesic modality because it is easy to perform and relatively safe. However, the effect of serratus plane block during intraoperative period has not yet been studied.

In this study, therefore, the investigators decided to assess the effect of serratus plane block on intraoperative opioid consumption, emergence time and hemodynamic stability in patients undergoing video-assisted thoracic surgery.

Study Timeline

• Study Start: 2018-08-28
• Study First Submitted: 2018-10-18
• Study First Submitted QC: 2018-10-22
• Study First Posted: 2018-10-24
• Status Verified: 2019-02
• Last Update Submitted: 2019-02-26
• Last Update Posted: 2019-02-27
• Primary Completion: 2019-06
• Study Completion: 2019-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• American Society of Anesthesiologists physical status classification I-III for three port video-assisted thoracic surgery lobectomy under general anesthesia

Exclusion Criteria

• History of allergic reaction to local anesthetics, coagulopathy, local infection at the injection site, and systemic infection.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
General anesthesia only	General anesthesia only	Video-assisted thoracic surgery was performed under balanced general anesthesia without serratus plane block
Serratus plane block	Serratus plane block	The subjects were received serratus plane block in the regional-anesthesia unit out of operation room before induction of general anesthesia. And, video-assisted thoracic surgery was performed under balanced general anesthesia.

Primary Outcome Measures

Name	Time	Method
Intraoperative remifentanil consumption	through study completion, an average of 1 year	Intraoperative remifentanil consumption will be checked.

Secondary Outcome Measures

Name	Time	Method
Dose of rescue drugs used to control blood pressure and HR	through study completion, an average of 1 year	Dose of rescue drugs used to control blood pressure and HR will be checked
Systolic blood pressure	through study completion, an average of 1 year	Systolic blood pressure (mmHg) will be checked
Heart rate	through study completion, an average of 1 year	Heart rate (beats per minute) will be checked
Emergence time	through study completion, an average of 1 year	Emergence time is duration between the end of surgery and extubation. Emergence time will be checked.

Trial Locations

Locations (1)

Kyungpook national university hospital; 🇰🇷 Daegu, Korea, Republic of