The Effects of Ultrasound-guided Serratus Plane Block in Combination With General Anesthesia on Intraoperative Opioid Consumption, Emergence Time and Hemodynamic Stability During Video-assisted Thoracoscopic Lobectomy
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Intraoperative remifentanil consumption
Study Overview
Brief Summary
This study evaluates the effects of serratus plane block on intraoperative opioid consumption, emergence time and hemodynamic stability in patients undergoing video-assisted thoracic surgery.
Detailed Description
Thoracotomy is known as one of the most painful surgery. Thus, there is a development to reduce surgical stress in terms of operation technique, which is video-assisted thoracoscopic surgery. Although it has reduced postoperative pain and complications compared with thoracotomy, VATS is still quite painful operation.
Serratus plane block is a novel technique which provide analgesic effect for lateral chest wall by blocking lateral branch of intercostal nerve. It has been reported to be used for pain management including rib fracture, herpes zoster, and postoperative pain. It has become a popular analgesic modality because it is easy to perform and relatively safe. However, the effect of serratus plane block during intraoperative period has not yet been studied.
In this study, therefore, the investigators decided to assess the effect of serratus plane block on intraoperative opioid consumption, emergence time and hemodynamic stability in patients undergoing video-assisted thoracic surgery.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 20 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •American Society of Anesthesiologists physical status classification I-III for three port video-assisted thoracic surgery lobectomy under general anesthesia
Exclusion Criteria
- •History of allergic reaction to local anesthetics, coagulopathy, local infection at the injection site, and systemic infection.
Arms & Interventions
Serratus plane block
The subjects were received serratus plane block in the regional-anesthesia unit out of operation room before induction of general anesthesia. And, video-assisted thoracic surgery was performed under balanced general anesthesia.
Intervention: Serratus plane block (Procedure)
General anesthesia only
Video-assisted thoracic surgery was performed under balanced general anesthesia without serratus plane block
Intervention: General anesthesia only (Procedure)
Outcomes
Primary Outcomes
Intraoperative remifentanil consumption
Time Frame: through study completion, an average of 1 year
Intraoperative remifentanil consumption will be checked.
Secondary Outcomes
- Dose of rescue drugs used to control blood pressure and HR(through study completion, an average of 1 year)
- Systolic blood pressure(through study completion, an average of 1 year)
- Heart rate(through study completion, an average of 1 year)
- Emergence time(through study completion, an average of 1 year)
Investigators
Saeyoung Kim, MD, PhD
Associate professor
Kyungpook National University Hospital