A Single Centre, Retrospective Cohort Study on Post Analysis on the Link Between the Clinical Heart Rate and Outcomes During PCI
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 15,000
- 主要终点
- Proportion of patients with composite events including CVD mortality, fatal/non-fatal MI, non-fatal sudden cardiac arrest, fatal/non-fatal stroke and malignant arrhythmia
研究概览
简要总结
The trial is a single centre, retrospective cohort, non-interventional study to be conducted in the department of cardiology, Chinese PLA General Hospital, Beijing, China. To evaluate the link between mean perioperative clinical heart rate and short-term composite outcomes during PCI among local CHD patients.
详细描述
The study requires those data including subjects aged from 20 to 80 year-old, diagnosed as coronary heart disease with records on mean clinical heart rate during PCI from 2009.1 to 2014.5 in the database from the department of cardiology, Chinese PLA General Hospital, Beijing. All 15,000 subjects' related data from the database will be collected.Once selected, 15,000 patients in the retrospective cohort will be divided into 4 groups according to their mean clinical resting heart rate during PCI. Group 1 will be defined as subjects' mean clinical resting heart rate ≤70 BPM, which will be set as baseline. Group 2 will be defined as subjects' mean clinical resting heart rate between 71 to 80 BPM. Group 3 will be defined as subjects' mean clinical resting heart rate between 81 to 90 BPM. Group 4 will be defined as subjects' mean clinical resting heart rate >90 BPM. The primary endpoint is to determine the link between the mean perioperative heart rate and short-term outcomes during PCI among local CHD patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients consecutive enrolled in Chinese PLA General Hospital from January 2009 to May 2014
- •Diagnosed as coronary heart disease with records on mean clinical heart rate during PCI .
排除标准
- •Inferior wall myocardial infarction (MI) history or/and acute inferior wall MI patients;
- •Dead within 3 days after admit into wards;
- •LVEF<30%;
- •Install a permanent pacemaker patients.
结局指标
主要结局
Proportion of patients with composite events including CVD mortality, fatal/non-fatal MI, non-fatal sudden cardiac arrest, fatal/non-fatal stroke and malignant arrhythmia
时间窗: During PCI
次要结局
- Mean perioperative clinical heart rate(During PCI)
- Clinical resting heart rate and heart rate variability(During PCI)
研究者
Dandan Li
M.D.
Chinese PLA General Hospital