Human Skin Aging: Clinical Parameters and Gene Expression Profiling
Completed
- Conditions
- Ageing
- Registration Number
- NCT01451476
- Lead Sponsor
- Stanford University
- Brief Summary
Skin aging is a complex process involving genetic and environmental factors. The investigators hope to learn more about how human genes and their function can contribute to skin aging and human health.
- Detailed Description
This study includes answering a survey on prior sun exposures, donating two small pieces of skin (4mm each), one blood draw, complexion analysis, photographs, and non-invasive tests such as skin surface lipid analysis. Your blood and tissue will be sent for DNA analysis and gene expression profiling.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 122
Inclusion Criteria
- healthy female, age 18 or older,
- Fitzpatrick type 1 or 2 skin,
- able to read and understand written consent form,
- body mass index normal or overweight range,
- willing to take blood tests and donate skin samples
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Exclusion Criteria
- pregnant or lactating,
- history of cosmetic surgery affecting the face,
- use of prescription anti-aging medications for 2 weeks prior to study,
- use of dietary supplements for 2 weeks prior to study, use of tanning beds or excessive light exposure (>2 hours) in the past 2 weeks,
- medical conditions which at the discretion of the investigator will have significant impact on ability to judge subjects' skin characteristics and age, sunless tanner use in past 2 weeks
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assessment of age related gene expression changes in skin Cross sectional
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Stanford Dermatology
🇺🇸Redwood City, California, United States