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Risk Factors of Ascending Aortic Atheromatous

Completed
Conditions
Ascending Aortic Atheromatous Plaque
Registration Number
NCT03381222
Lead Sponsor
Mahidol University
Brief Summary

Background Incidence of perioperative stroke In cardiac surgery is 2.6-5.2%. Ascending aortic atheromatous plaque and stroke are strongly associated.

Propose of study To determine incidence of ascending aortic atheroma in Thai people To identify risk factors which associated with ascending aortic atheroma

Methodology After received standard general anesthesia and start sternotomy. Epiaortic scan will be performed by surgeon use L15-7i Phillips® ultrasound probe cover with sterile cover.

Five standard epiaortic views will be collected. Epiaortic clips will be review and determine about atheroma by two qualified echocardiographers. Atheroma more than third grade will defined to significant. Potential risk factors of atheroma will be gather from medical record

To assess the relationship between risk factors and atheroma a univariate analysis was performed using an unpaired t-test and a Chi-square test.

For higher accuracy regarding the impact of single risk factors, a multiple logistic regression analysis was also performed.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
239
Inclusion Criteria

Age ≥ 18 years Schedule to cardiac surgery with sternotomy

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Exclusion Criteria

Abnormal ascending aortic anatomy such as: dissection, aneurysm

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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Incidence of ascending aortic atheromatous plaque in Thai population1 year

incidence of ascending aortic atheromatous plaque

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

faculty of medicine Siriraj hospital

🇹🇭

Bangkok Noi, Bangkok, Thailand

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