Risk Factors of of Ascending Aortic Atheromatous Plaque in Thai Cardiac Surgical Patient
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 239
- 试验地点
- 1
- 主要终点
- Incidence of ascending aortic atheromatous plaque in Thai population
研究概览
简要总结
Background Incidence of perioperative stroke In cardiac surgery is 2.6-5.2%. Ascending aortic atheromatous plaque and stroke are strongly associated.
Propose of study To determine incidence of ascending aortic atheroma in Thai people To identify risk factors which associated with ascending aortic atheroma
Methodology After received standard general anesthesia and start sternotomy. Epiaortic scan will be performed by surgeon use L15-7i Phillips® ultrasound probe cover with sterile cover.
Five standard epiaortic views will be collected. Epiaortic clips will be review and determine about atheroma by two qualified echocardiographers. Atheroma more than third grade will defined to significant. Potential risk factors of atheroma will be gather from medical record
To assess the relationship between risk factors and atheroma a univariate analysis was performed using an unpaired t-test and a Chi-square test.
For higher accuracy regarding the impact of single risk factors, a multiple logistic regression analysis was also performed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years Schedule to cardiac surgery with sternotomy
排除标准
- •Abnormal ascending aortic anatomy such as: dissection, aneurysm
结局指标
主要结局
Incidence of ascending aortic atheromatous plaque in Thai population
时间窗: 1 year
incidence of ascending aortic atheromatous plaque
次要结局
未报告次要终点
研究者
Chaowanan Khamtuikrua
principal investigator
Mahidol University
