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Preliminary study on the role of local chronic inflammation in persistent work-related complaints in the arm/hand area during heavy occupational stress

Conditions
Z87.3
Personal history of diseases of the musculoskeletal system and connective tissue
Registration Number
DRKS00031872
Lead Sponsor
Institut für Arbeitsmedizin, Sozialmedizin und Versorgungsforschung, Universitätsklinikum Tübingen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
40
Inclusion Criteria

Employment: a minimum of one year employment to above described workplaces at the time of study inclusion.

Musculoskeletal pain: the study population should suffer from varying degrees of musculoskeletal pain in the elbow/forearm/hand-area, which will be assessed using the Cornell Musculoskeletal Discomfort Questionnaire (Kreuzfeld et al. 2016).

Exclusion Criteria

Status after accident and/or systemic diseases that affect joints or muscles and/or are associated with acute and chronic inflammations.

Musculoskeletal pain that is not localized in the elbow/forearm/hand-area and that is equally or more severe than in the elbow/forearm/hand-area examined in the current study, as assessed by the Cornell Musculoskeletal Discomfort Questionnaire (Kreuzfeld et al., 2016).

Relative and absolute contraindications for repeated blood sampling, such as: fear of blood sampling (relative), taking anticoagulants (absolute), few suitable veins that should only be used for therapeutic interventions (absolute).

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Reliability of the inflammatory biomarkers (i.a.) IL-1ß, IL-6 and CRP
Secondary Outcome Measures
NameTimeMethod
Musculoskeletal upper-extremity pain<br>Clinical signs of chronic musculoskeletal upper-extremity disorders
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