Efficacy of Ayurvedic Formulation (Mansyadi Kwath) in the Management of Hypertension (Uccha Raktachapa): A Randomised Open Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Treatment with Mansyadi Kwath may result in a significant reduction in blood pressure, with an expected fall of 10–15 mmHg in mean value of systolic BP and 5–10 mmHg in mean value of diastolic BP, indicating potential clinical benefit in hypertension management.
研究概览
简要总结
Background: Over one-fifth of the global adult population is affected by elevated blood pressure, while cardiovascular diseases contribute to around 17 million deaths annually, representing nearly one-third of all deaths worldwide. Ayurvedic treatments play a significant role in effectively alleviating the signs and symptoms of such diseases. Masyadi Kashaya, with its specific ingredients, acts on the root cause of the condition and helps in its management. Aims & Objective - This study aims to evaluate the therapeutic efficacy of Mansyadi Kwath in the management of Uccha Raktachapa w.s.r. to Hypertension (HTN).
Material and Methods: Randomized open clinical trial of Masyadi Kwatha was done on population size of 80, for the period of one month and assesd befor and after the treatment. Result and Discussion: Response of the intervention has been defined in lieu of improvement in the Sign & Symptoms along with subjective and objective parameters. The trial drug Mansyadi Kwath was well tolerated having no patients force to discontinue out of drug intolerance. The Clinical assessment of results shows that, Maximum number of patients 56 (70%) got moderate improvement and only 24 (30%) of patients got mild improvement after 30 days of treatment.
Conclusion: Masyadi Kwatha shows excellent improvement in assessment parameters, supported by statistical data, Mansyadi Kwatha can be effectively used alongside standard treatment, contributing significantly to the management and improvement of Hypertension.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 35.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Essential Hypertensive patients having systolic blood pressure less then 160 and diastolic blood pressure less than 100 mmHg.
排除标准
- •Hypertension with IHD, CHD, CAD, Coarctationof aorta, Renal failure, Endocrine diseases, Cerebral complications e.g. hypertensive encephalopathy, cerebral haemorrhage, convulsive seizure.
- •Hypertensive patient having systolic blood pressure more than 160 and diastolic more than 100 mmHg. Pregnant lady.
结局指标
主要结局
Treatment with Mansyadi Kwath may result in a significant reduction in blood pressure, with an expected fall of 10–15 mmHg in mean value of systolic BP and 5–10 mmHg in mean value of diastolic BP, indicating potential clinical benefit in hypertension management.
时间窗: BP will be assessed on 1st and 30th day.
次要结局
未报告次要终点
研究者
Dr SANJAY YADAV
Major S.D. Singh P.G. Ayurvedic Medical College and Hospital