Advanced Hemodynamic Monitoring for Goal-directed Hemodynamic Management During Radical Cystectomy

Not Applicable

• Conditions: Radical Cystectomy; Perioperative Complications; Hemodynamic Monitoring
• Interventions: Other: Increasing oxygen delivery .

• Registration Number: NCT00966147
• Lead Sponsor: Hadassah Medical Organization

Brief Summary

The purpose of this study is to determine whether increasing cardiac output by a combination of intravenous fluids and inotropic drugs can reduce mortality and morbidity in radical cystectomy operations.

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-07
• Study First Submitted: 2009-08-25
• Study First Submitted QC: 2009-08-25
• Last Update Submitted: 2009-08-25
• Study First Posted: 2009-08-26
• Last Update Posted: 2009-08-26
• Study Start: 2009-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Adults (>18yo) scheduled for elective radical cystectomy and ileal conduit formation

Exclusion Criteria

• Creatinine level above 200 mcg/dl
• single functioning kidney
• s/p kidney transplant
• heart rhythm other than sinus
• known allergy to lithium chloride
• chronic lithium therapy
• weight below 40 kg
• mental or language problems that precludes obtaining informed consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Lidco group	Increasing oxygen delivery .	All patients monitored by the lidco system and treated to optimize oxygen delivery

Primary Outcome Measures

Name	Time	Method
Mortality	Hospital stay

Secondary Outcome Measures

Name	Time	Method
Morbidity	Hospital stay

Trial Locations

Locations (1)

Hadassah Medical Organization, Jerusalem, Israel; 🇮🇱 Jerusalem, Israel