A study to compare the effect of Morphine (an opioid) versus Butorphanol ( an opioid) in surgeries below umbilicus performed under anesthesia

Not Applicable

• Conditions: Health Condition 1: O- Medical and Surgical

• Registration Number: CTRI/2021/05/033800
• Lead Sponsor: Office of Principal Midnapore Medical College and Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

CASES WITH ASA GRADE I AND II

CASES WITH HEIGHT BETWEEN 150 TO 180 CMS AND BODY WEIGHT BETWEEN 50 TO 80 KG, BMI BETWEEN 18.5 AND 24.9

CASES UNDERGOING INFRAUMBILICAL SURGERY THAT ARE PERFORMED UNDER SUBARACHNOID BLOCK

Exclusion Criteria

CASES WHICH HAVE CONTRAINDICATION FOR SPINAL ANESTHESIA

CASES WITH ASA GRADE III AND ABOVE

PREGNANT AND LACTATING PATIENTS

PATIENTS WITH PSYCHIATRIC ILLNESS

CASES WITH HISTORY OF HYPERSENSITIVITY OR ALLERGY TO STUDY DRUGS

CASES WITH NEUROPATHY OR NEUROLOGICAL DISORDER

PATIENTS WITH ANY ONGOING THERAPIES WITH SUSTAINED RELEASE OPIOIDS

ANY PATIENT WITH CARDIORESPIRATORY OR HEPATORENAL DISORDERS

IMMUNOCOMPROMISED AND DIABETIC PATIENTS

ANY PATIENT REQUIRING ANALGESIC OR ANESTHETIC SUPPLEMENTATION INTRAOPERATIVELY

ANY PATIENT CONVERTED TO GENERAL ANESTHESIA ANYTIME AFTER GIVING SPINAL ANESTHESIA , TILL COMPLETION OF SURGERY

ANY UNFORESEEN LIFE THREATENING COMPLICATIONS DUE TO SURGERY OCCURING ANYTIME PERIOPERATIVELY

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
TO ASSESS THE DURATION OF ANALGESIA OF MORPHINE AND BUTORPHANOL INTRAOPERATIVELY AND POSTOPERATIVELY UPTO 12 HOURSTimepoint: TO ASSESS THE DURATION OF ANALGESIA OF MORPHINE AND BUTORPHANOL INTRAOPERATIVELY AND POSTOPERATIVELY UPTO 12 HOURS

Secondary Outcome Measures

Name	Time	Method
1. HEMODYNAMIC PARAMETERS LIKE HEART RATE, SYSTOLIC BLOOD PRESSURE, DIASTOLIC BLOOD PRESSURE, MEAN BLOOD PRESSURE,Timepoint: PARAMETERS WILL BE NOTED JUST BEFORE ENTERING OT, FOLLOWED BYEVERY 5 MINUTES FOR 30 MINUTES AND 15 MINUTES THEREAFTER TILL COMPLETION OF SURGERY AND FIRST 2 HOURS POSTOPERATIVELY;SEDATION AND OTHER SIDE EFFECTSTimepoint: ASSESSED EVERY 15 MINUTES INTRAOPERATIVELY AND AFTER SURGERY FOR FIRST 2 HOURS AND 30 MINUTES THEREAFTER TILL 12 HOURS POSTOPERATIVELY;SENSORY AND MOTOR BLOCKADETimepoint: BLOCK CHARACTERISTICS WILL BE NOTED TILL SUCCESSFUL INITIATION OF SENSORY AND MOTOR BLOCK AND EVERY 15 MINUTES AFTER SURGERY FOR FIRST 2 HOURS AND 30 MINUTES THEREAFTER TILL 12 HOURS POSTOPERATIVELY;SURGICAL RELAXATIONTimepoint: ASKED FROM MAIN SURGEON AT END OF SURGICAL CLOSURE