Assessment of Interstitial Lung Disease in Rheumatoid Arthritis by Lung Ultrasound
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 34
- 试验地点
- 1
- 主要终点
- Sensibility and specificity of the lung sonography for interstitial lung disease screening in rheumatoid arthritis patients.
研究概览
简要总结
The high resolution chest scan is the gold standard for the screening of interstitial lung disease, but this remains an onerous examination, and irradiating.
Ultrasound could be used to detect these disorders with a very good sensitivity and specificity. This exam offers the advantage of being non radiating, inexpensive, and accessible to the rheumatologist who already uses it in their daily practice.
The investigators want to assess the lung ultrasound performance compared with the gold standard.
Patients will be included during a regular follow-up consultation with their referent rheumatologist. If there is an indication of first line biotherapy or targeted therapy the doctor will propose to the patient to participate in the study, give him the information leaflet, collect orally non-opposition, and will complete a survey for evaluation of the general health and potential risk factors for interstitial lung.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men and women over the age of 18
- •With rheumatoid arthritis meeting the criteria ACR (American College of Rheumatology)/ EULAR (EUropean League Against Rheumatism) 2010
- •Never received any biotherapy or targeted therapy
- •Having an indication of introduction of biotherapy or therapy targeted (JAK inhibitors) (JAK : Janus kinase)
排除标准
- •Refusal to participate in the study
- •Known pulmonary disease that can alter lung interstitium: cardiac decompensation, COPD (chronic obstructive pulmonary disease), thoracic surgery, infection pulmonary
- •Patient with respiratory functional signs suggestive of PID (Diffuse interstitial lung disease)
- •Patient with signs of cardiac decompensation
- •Patient with pulmonary auscultation suggestive of PID
- •Pregnant or lactating woman
- •Psychiatric pathology seriously hindering understanding
- •Difficulty understanding oral French
- •Person deprived of liberty or under legal protection
结局指标
主要结局
Sensibility and specificity of the lung sonography for interstitial lung disease screening in rheumatoid arthritis patients.
时间窗: Month 12
To estimate the sensitivity and specificity of pulmonary ultrasound compared to CT scans in patients with rheumatoid arthritis consulting at the Lyon South Hospital Centre or the Edouard Herriot Hospital for the start-up of biotherapy or targeted therapy. (CT : computerized tomography)
次要结局
未报告次要终点