Evaluation of the effect of enemas with a lipid solution to mobilize meconium in preterm infants

Completed

• Conditions: P76; P78; Other intestinal obstruction of newborn; Other perinatal digestive system disorders

• Registration Number: DRKS00024021
• Lead Sponsor: niversitätsklinikum Tübingen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-02
• Study Completion: 2021-07-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 399

Inclusion Criteria

Preterm infants with gestational age < 28 0/7 SSW or < 32 0/7 SSW with concomitant hypotrophy (GG < 10th percentile) and treatment within the first 24 hours of life at the study site

Exclusion Criteria

Congenital gastrointestinal malformation, inborn errors of metabolism, pre-determined palliative care

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rate of intestinal perforations and before and after the introduction of lipid enemas

Secondary Outcome Measures

Name	Time	Method
Time in days until full enteral feeds<br>Time in days with a peripheral or central venous catheter for (partial) parenteral nutrition<br>Number and composition of applied enemas<br>Stool patterns in the first days of life<br>Rate of necrotizing enterocolitis