Effect of three different ticagrelor loading dose formulations (crushed, chewed or intact tablets) on the degree and rapidity of platelets ability to clump together and form clots in patients with stable angina referred for coronary angiography

• Conditions: Effect of three ticagrelor loading dose formulations on the degree and rapidity of platelet aggregation in patients with stable angina referred for coronary angiography; Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]

• Registration Number: EUCTR2014-002227-96-SE
• Lead Sponsor: County Council of Östergötland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-07-29
• Last Update Posted: 14 March 2016

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Patients with stable angina referred for coronary angiography
Ability to provide informed consent
Age 18 years or older
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 50
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 50

Exclusion Criteria

Pregnacy or lactation, chronic therapy with ticagrelor, prasugrel, clopidogrel or ticlopidine, treatment with warfarin or NOAC in the last 4 days, active bleeding or increased risk of bleeding, history of gastrointestinal or geniourinary bleeding in the last 2 months, history of intracranial bleeding, major surgery in the last 4 weeks, severe anaemia or thrombocytopenia, severe liver or renal disease, increased risk of bradycardia, unable to chew tablet.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified