Evaluation of the Effect of Serratus Anterior Block and Erector Spinae Block on Postoperative Analgesia in Thoracic Surgeries
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- total morphine consumption in first postoperative 24 hours
研究概览
简要总结
90 patients scheduled for thoracic cancer surgeries, allocated in 3 groups for serratus anterior block and erector spinae block and control group. during anaesthesia:total intraoperative fentanyl required will be recorded. After surgery, all patients will be connected to PCA device containing morphine solution, the amount of morphine consumed during the first 24 hours will be recorded.
详细描述
90 patients scheduled for thoracic cancer surgeries, allocated in 3 groups for serratus anterior block (SAB) and erector spinae block (ESB) and control group. During anaesthesia: total intraoperative fentanyl required will be recorded. After surgery, all patients will be connected to PCA device containing morphine solution, the amount of morphine consumed during the first 24 hours will be recorded. Other secondary outcomes are: numerical rating scales and postoperative pulmonary functions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with class II physical status (American Society of Anaesthesiologists) ,
- •Age between 18-70 years,
- •Scheduled for thoracic cancer surgery
排除标准
- •Patient refusal.
- •Local infection at the site of the block.
- •Cardiac dysfunction (ejection fraction <45%).
- •Significant respiratory disorders.
- •Preexisting neurological or psychiatric disease.
- •Allergy to one of the study drugs.
- •Pregnancy.
- •Coagulopathy
研究组 & 干预措施
serratus anterior block
serratus anterior block with 20 ml bupivacaine
干预措施: Serratus anterior block (SAB) (Procedure)
serratus anterior block
serratus anterior block with 20 ml bupivacaine
干预措施: Bupivacaine (Drug)
erector spinae block
erector spinae block with 20 ml bupivacaine
干预措施: Erector spinae block (Procedure)
erector spinae block
erector spinae block with 20 ml bupivacaine
干预措施: Bupivacaine (Drug)
control group
sham block with 20 ml saline
干预措施: Saline (as a placebo) (Drug)
结局指标
主要结局
total morphine consumption in first postoperative 24 hours
时间窗: first 24 postoperative hours
the amount of morphine required to relieve pain will be recorded
次要结局
- numerical rating scale(the first 24 postoperative hours)
- pulmonary functions(24 hours after surgery)
- intraoperative fentanyl requirement(during anaesthesia)