Effects of Inspiratory Muscle Training on Respiratory Muscle Strength, Diaphragm Thickness, and Diaphragm Excursion in Mechanically Ventilated Intensive Care Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Respiratory muscle strengh
研究概览
简要总结
In addition to conventional chest physiotherapy, inspiratory muscle training will be applied in mechanically ventilated intensive care patients. It is aimed to examine the effects of inspiratory muscle training on respiratory muscle strength, diaphragm thickness, and diaphragm excursion in intubated or tracheostomized patients with mechanical ventilation in the intensive care unit.
详细描述
Subjects who mechanically ventilated in the intensive care unit will be divided two groups. Study group will recieve inspiratory muscle training in addition to convantional chest physiotherapy. Control group will recieve convantional chest physiotherapy. Training will continue until discharge or until the 21st day of the training. Respiratory muscle strength, diaphragm thickness and diaphragm excursion were measured before training and before discharge.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •≥18 years of age
- •hemodynamic stability and alert
- •able to spontaneously trigger the ventilator and perform at least one command for activation of respiratory muscles
- •required mechanical ventilation support with continuous spontaneous ventilation mode or pressure- or volume-controlled intermittent mandatory ventilation (6 breaths/min) mode
- •required pressure support ≤ 15 cmH2O and PEEP ≤ 10 cmH2O
- •unable to breathe without support for 72 consecutive hours following the resolution of factors leading to respiratory failure
- •FiO2 of 0.5 or less
- •PaO2 greater than 60 mmHg and capable of sufficient gas exchange
排除标准
- •cooperation disorder
- •trauma or deformity related to the thorax that affect respiration
- •progressive neuromuscular disease
- •excessive bronchial secretion (requiring more than one suctioning per hour)
- •need for continued sedative or analgesic agents
- •use of home-type mechanical ventilation before admission to the hospital
- •cardiac, pulmonary, or other conditions leading to impaired stability
- •impaired cooperation, compliance, and motivation
结局指标
主要结局
Respiratory muscle strengh
时间窗: 20 minutes
Respiratory muscle strength was measured as maximal inspiratory pressure.
Diaphragm thickness
时间窗: 15 minutes
Diaphragm thickness was evaluated using ultrasound imaging in two-dimensional B mode (4-13 MHz) performed from the midaxillary level from the right intercostal space with patients sitting in a position as upright as possible. The thickness of the diaphragm was ensured with the superficial probe at end-inspiration (Tins) and end-expiration (Texp).
Diaphragm excursion
时间窗: 20
Diaphragm excursion was evaluated at the midaxillary level from the right subcostal area with M-mode (2-5 MHz) ultrasonography in normal inspiration and deep inspiration.
次要结局
- Physical Function in Intensive Care Test (PFIT)(20 minutes)
- Duration of intubation(3-15 days)
- Extubation rate(3-15 days)
- Rate of discharge from the intensive care unit(8-21 days)
研究者
Harun Taşkın
Assistant Professor
Afyonkarahisar Health Sciences University