NCT03241472已完成3 期
Induction of Ovulation Using Clomiphene Citrate and N-acetyl Cysteine Versus Letrozole
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 100
- 主要终点
- rate of ovulation
研究概览
简要总结
Infertility is defined as a couple's inability to become pregnant after one year of unprotected intercourse in women 35 years old and younger, and for six months in women over age 35 years. In any given year, about 15 percent of couples in North America and Europe who are trying to conceive are infertile
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All primary and secondary. Infertility due to anovulation
排除标准
- •Male factor infertility, tubal factor.
- •Endocrineopathy
- •Hypothyrodism
- •Morbid obesity
- •Under weight
- •Patient with previous surgery including drilling of ovary, Clomiphene Citrate resistant to ovulation.
研究组 & 干预措施
Lertozole
Experimental
oral tablets 5 mg start from third day cycle for 5 days
干预措施: Letrozole (Drug)
clomiphene plus N- acetyl cystiene
Active Comparator
clomiphene 100 mg plus N-acetyl cystiene 600 mg start from third day cycle for 5 days
干预措施: Clomiphene Citrate plus N acetyl cystine (Drug)
结局指标
主要结局
rate of ovulation
时间窗: 3 months
ultrasound evaluation
次要结局
未报告次要终点
研究者
Ahmed Mohamed Abbas
principal investigator
Assiut University
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