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The effect of rehabilitation on respiratory symptoms and lung function indexes

Not Applicable
Recruiting
Conditions
Asthma.
J45
Asthma
Registration Number
IRCT20180418039348N2
Lead Sponsor
Mashhad University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

Mild to moderate bronchial asthma disease based on spirometric testing and having clinical symptoms of respiratory tract
Absence of acute illnesses that are in contradiction with exercise
Age limit 20 to 60 years
Giving written consent
Having a commitment to doing research steps

Exclusion Criteria

Severe asthma that is exacerbated by exercise
Acute diseases that are exacerbated by exercise
Cardiovascular disease
Chronic inflammatory diseases
Acute infections
Malignant diseases
Having autoimmune diseases and immune deficiency

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Improvement in respiratory status and spirometry tests. Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Measurement with using a spirometer device and pulmonary function tests.;Measuring cytokines and inflammatory mediators ( such as IgE ? IgG TNFa, IL-6 and IL-8 ) in serum. Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Use of special kits and protocols.;Total number and types of white blood cells in the blood. Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Using a special laboratory device for counting white blood cells.
Secondary Outcome Measures
NameTimeMethod
Measurement concentration of fractional exhaled nitric oxide (FeNO). Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Use of special kits and protocols.;Measurement of C-reactive protein (CRP). Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Use of special kits and protocols.
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