The effect of rehabilitation on respiratory symptoms and lung function indexes
Not Applicable
Recruiting
- Conditions
- Asthma.J45Asthma
- Registration Number
- IRCT20180418039348N2
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Mild to moderate bronchial asthma disease based on spirometric testing and having clinical symptoms of respiratory tract
Absence of acute illnesses that are in contradiction with exercise
Age limit 20 to 60 years
Giving written consent
Having a commitment to doing research steps
Exclusion Criteria
Severe asthma that is exacerbated by exercise
Acute diseases that are exacerbated by exercise
Cardiovascular disease
Chronic inflammatory diseases
Acute infections
Malignant diseases
Having autoimmune diseases and immune deficiency
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement in respiratory status and spirometry tests. Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Measurement with using a spirometer device and pulmonary function tests.;Measuring cytokines and inflammatory mediators ( such as IgE ? IgG TNFa, IL-6 and IL-8 ) in serum. Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Use of special kits and protocols.;Total number and types of white blood cells in the blood. Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Using a special laboratory device for counting white blood cells.
- Secondary Outcome Measures
Name Time Method Measurement concentration of fractional exhaled nitric oxide (FeNO). Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Use of special kits and protocols.;Measurement of C-reactive protein (CRP). Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Use of special kits and protocols.