Sericin cream reduces pruritis in hemodialysis patients

Completed

• Conditions: remic pruritus in hemodialysis patients; Skin and Connective Tissue Diseases; Pruritus, unspecified

• Registration Number: ISRCTN16019033
• Lead Sponsor: ational Research Council (Thailand)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-02-16
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. All patients over 18 years of age with chronic kidney disease (CKD)
2. Patients who had received hemodialysis for at least three months were screened for this study
3. Mild to severe pruritis, according to the VAS, during the previous 6 weeks
4. Patients had to be willing to refrain from any antipruritic treatment, oral or topical, for a period of not less than 2 weeks prior to the start of the study.
5. Patients of both genders, regardless of comorbidities or prescribed medications

Any medication that had antipruritic effect was discontinued 1 week before the study. No change in the medication prescription of patients was required during this study, with the exception of concomitant antipruritic treatment.

Exclusion Criteria

1. Causes of pruritis from any other skin disease or from any medication
2. Patients with a history of silk protein allergy or who were allergic to any compounds in the formula
3. Patients who had biliary atresia, liver problems, cancer, metabolic disorders or other diseases related to systemic pruritis
4. Participants also left the project when they could not comply with the treatment, were unwilling to continue with the study or when the physician opined that other treatments were needed to relieve the symptoms.

Study & Design

• Study Type: Interventional
• Study Design: Not specified