ACTRN12620000807954
Recruiting
未知
REstoring microvascular circulation with Diagnostic Ultrasound and Contrast agEnt (REDUCE): A multicentred, randomised, double blinded, controlled trial in patients presenting with ST elevation myocardial infarction.
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Ischaemic Heart Disease
- Sponsor
- niversity of Sydney
- Enrollment
- 150
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Chest Pain with ST segment elevation \>0\.1 mV in two contiguous leads, or ST segment depression \>0\.2mV in two contiguous leads V1\-V3 (consistent with a posterior STEMI)
- •\- Eligible for emergent PCI/antithrombotic/antiplatelet therapy.
- •\- Adequate apical and/or parasternal images by echocardiography.
- •\- No contraindications or hypersensitivities to ultrasound contrast agents.
Exclusion Criteria
- •\- Unable to provide written consent to participate in the trial
- •\- Chest pain lasting \>6 hours
- •\- Cardiogenic shock
- •\- Fibrinolytic therapy prior to arrival in the emergency department
- •\- Life expectancy of less than six months from any other co\-morbidity or terminally ill
- •\- Prior ST\-segment elevation myocardial infarction (STEMI)
- •\- Known or suspected hypersensitivity to perflutren, the contrast agent used for the study
- •\- Known cardiomyopathy
- •\- Known severe valvular heart disease
- •\- Known bleeding diathesis or contraindication to glycoprotein 2b/3a inhibitors, anticoagulants, or aspirin
Outcomes
Primary Outcomes
Not specified
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