Behavioral Economics and Implementation Research to Reduce Cardiovascular Risk in HIV-Infected Adults
试验速览
- 阶段
- 不适用
- 入组人数
- 75
- 试验地点
- 8
- 主要终点
- Change in proportion of PLWH with cardiovascular risk factors seen by a physician receiving statin therapy
研究概览
简要总结
Cardiovascular disease is a major cause of morbidity and mortality among people living with HIV. Recent studies have demonstrated that patients with HIV experience a 50-100% increased risk of myocardial infarction and stroke compared to HIV-uninfected persons. They also face higher risks of stroke, sudden death, and heart failure. However, evidence-based statin therapy-which is safe in this population and highly effective at reducing cardiovascular risk-is under-prescribed. The investigators propose a multi-level intervention to increase evidence-based statin prescribing by addressing barriers at these levels. The implementation intervention includes two strategies: (1) tailored education at the leadership, provider, and patient levels, and (2) behavioral economics-informed feedback for providers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age ≥ 40 years
- •have been diagnosed with HIV
- •LDL ≥ 190, diabetes and LDL ≥ 70
- •or 10-year ASCVD risk ≥ 7.5%
- •or history of heart attack, stroke, or peripheral vascular disease
- •care for patients with HIV at least 1/2 day each week (physicians)
- •work at participating clinics (physicians)
排除标准
- •unable to provide written, informed consent
- •not at participating clinic
研究组 & 干预措施
Patient Level
干预措施: Knowledge assessment (Behavioral)
Organization Level
干预措施: Knowledge assessment (Behavioral)
Provider Level
干预措施: Knowledge assessment (Behavioral)
Provider Level
干预措施: Education Intervention (Behavioral)
Provider Level
干预措施: Provider Feedback (Behavioral)
结局指标
主要结局
Change in proportion of PLWH with cardiovascular risk factors seen by a physician receiving statin therapy
时间窗: 12 months
次要结局
未报告次要终点
研究者
Allison L. Diamant
Principal Investigator
University of California, Los Angeles