Phase 1 Study of Inhaled Carbon Monoxide on the Effectiveness of Neonatal Pulmonary Hypertension
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Number of participants with adverse events
研究概览
简要总结
Based on the study about carbon monoxide in human inflammatory and other beneficial physiological function , now we'll be going to research its application in neonates .Phase 1 Study as a foundation for the further test is, the safety and Adverse reaction study of newborn to inhaled CO
详细描述
Previous studies have demonstrated that, carbon monoxide has showed the effectiveness such as in inflammation ,apoptosis as well as relaxation of smooth muscle of the body. Now we have a hypothesis to use carbon monoxide in pulmonary hypertension of the newborns, to observe whether it will decrease pulmonary artery hypertension on newborns. Phase 1 study is ,the safety and Adverse reaction study of newborn to inhaled CO , after this,we can master the application of carbon monoxide dose
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 1 Minute 至 1 Month（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •The newborn whose physiological function is healthy or close to healthy
排除标准
- •Clinical considerations cannot survive or no treatment value of newborn Diagnosis of congenital or hereditary diseases, or children with heart diseaseCentral pulmonary vascular malformations in children
结局指标
主要结局
Number of participants with adverse events
时间窗: up to 1 month
次要结局
未报告次要终点
研究者
CAN WANG
Phase 1 Study of Inhaled carbon monoxide on the effectiveness of neonatal pulmonary hypertension
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University