A pilot study to investigate the role of androgens in the sexual functioning of women with primary ovary insufficiency (POI).
- Conditions
- POI, POF, sexual dysfunction
- Registration Number
- NL-OMON28298
- Lead Sponsor
- AMC, Amsterdam
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
1. Participating in the POI-trial in Utrecht;
2. Being treated for POI at the AMC, Amsterdam.
Exclusion Criteria
1. Oophorectomy;
2. Severe relationship problems.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hormone levels:<br /><br>1. Estradiol;<br /><br>2. Total testosterone;<br /><br>3. Bio-available testosterone;<br /><br>4. SHBG;<br /><br>5. Androstenedione;<br /><br>6. Dehydroepiandrosterone sulfate.<br><br /><br /><br>Sexual function:<br /><br>1. Genital response by VPA;<br /><br>2. Subjective response by questionnaires, FSFI & FSDS-R.<br><br /><br /><br>Implicit association tasks:<br /><br>1. stIAT;<br /><br>2. PAT;<br /><br>3. Dot detection task.
- Secondary Outcome Measures
Name Time Method The feasibility of these tests in this group, measured by interview.