Evaluation of Macular Vascular Changes in Behcet's Disease Using Optical Coherence Tomography Angiography
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Assiut University
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Qualitative description of the retinal capillary plexus changes in the macular area
Study Overview
Brief Summary
Behcet's disease is an important cause of retinal vasculitis and vision loss in Egypt. Fluorescein angiography is the standard method of diagnosis of retinal vasculitis. OCT angiography (OCT-A) is a recently developed method that can be used in the evaluation of retinal circulation. In this study, we will test the utility of OCT-A in diagnosis and follow up of retinal vascular changes in cases diagnosed with Behcet's disease that visit the outpatient uveitis clinic of Assiut University hospital, a major tertiary center in southern Egypt, over a one year duration. Also, correlation of OCT-A changes with visual acuity and hence prognosis will be described.
Detailed Description
Aim of the research To describe macular retinal vascular changes in patient with retinal vasculitis secondary to Behcet's disease both qualitatively and quantitatively.
Research design Type of the study: cross sectional analytical study Study Setting: Assuit University Hospital (Ophthalmology Department)
Study subjects:
- Inclusion criteria:
• Patients diagnosed with Behcet's disease with or without active uveitis 2. Exclusion criteria:
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •• Patients diagnosed with Behcet's disease
Exclusion Criteria
- •• Patients less than 18 years old
- •Hazy media precluding clear fundus view.
- •Patients with very poor fixation.
Outcomes
Primary Outcomes
Qualitative description of the retinal capillary plexus changes in the macular area
Time Frame: 1 year
Secondary Outcomes
- Correlation between extent of macular vascular changes and visual acuity(1 year)
Investigators
Menatallah Saleh
Principal Investigator
Assiut University