Maternal Polyunsaturated Fatty Acids in Association With Child Autism Spectrum Disorder in the MARBLES Study

Completed

• Conditions: Autism Spectrum Disorder
• Interventions: Behavioral: Maternal Supplemental PUFA Intake

• Registration Number: NCT03468959
• Lead Sponsor: University of California, Davis

Brief Summary

This study is to examine the association between maternal omega3 and other polyunsaturated fatty acids (PUFAs) during pregnancy and autism spectrum disorder (ASD) as well as other non-typical development (Non-TD) in the prospective Markers of Autism Risk in Babies-Learning Early Signs (MARBLES) cohort.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design

Study Timeline

• Study Start: 2006-01
• Primary Completion: 2016-06-30
• Study Completion: 2016-06-30
• Status Verified: 2018-02
• Study First Submitted: 2018-02-09
• Study First Submitted QC: 2018-03-12
• Study First Posted: 2018-03-19
• Last Update Submitted: 2023-12-28
• Last Update Posted: 2023-12-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 252

Inclusion Criteria

• Mother or father had a biological child with ASD
• Mother is at least 18 years old
• Mother is pregnant or planning a pregnancy, and biologically able to become pregnant
• Mother is living within 2 hours of the MIND Institute
• Mother is sufficiently fluent in English

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Exclusion Criteria

• Mothers with diseases which will influence on their study participation

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Mother-child pairs	Maternal Supplemental PUFA Intake	Families were recruited from lists of children receiving autism services obtained via the California Department of Developmental Services (DDS), from other studies at the Medical Investigation of Neurodevelopmental Disorders (MIND) Institute, or by self-referrals. The inclusion criteria were: a) mother or father had a biological child with ASD, and the mother was b) at least 18 years old; c) pregnant or planning a pregnancy, and biologically able to become pregnant; d) living within 2 hours of the MIND Institute; e) sufficiently fluent in English.

Primary Outcome Measures

Name	Time	Method
autism spectrum disorder group (ASD)	36 months	number of people with ASD

Secondary Outcome Measures

Name	Time	Method
A group of typically development (TD) people	36 months	number of typically developed people