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临床试验/NCT03877354
NCT03877354招募中不适用

Comparison of Tidal Volume Between Pediatric Anaesthesia and Paediatric Intensive Care Patients: Retrospective Study

Brno University Hospital1 个研究点 分布在 1 个国家目标入组 1,000 人开始时间: 2019年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
1,000
试验地点
1
主要终点
Tidal volume

研究概览

简要总结

Paediatric anaesthesiology and paediatric intensive care unit data will be retrospectively screened for the data regarding mechanical ventilation. The primary aim will be the tidal volume setting and the secondary the level of positive end-expiration pressure (PEEP) according to the inspired oxygen fraction (FIO2), and the level of driving pressure.

详细描述

Protective positive pressure ventilation (tidal volume ≤6 mL/kg) in adult patients in intensive care is currently considered as a standard procedure. It is associated with a reduction of morbidity and positive outcome. In paediatric patients there are available only limited information related to the size of the tidal volume and it is recommended to use the volume between 5 and 8 mL per kg for the whole spectrum of ages of pediatric patients. The aim of this retrospective observational study is to evaluate the tidal volumes used in clinical practice in pediatric patients during general anesthesia and compared it to the tidal volumes used in paediatric critical care. Data will be harvested from the anaesthesiology records and from the paediatric intensive care unit charts. The tidal volume will calculated per kg of actual weight.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
— 至 19 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Paediatric patients on mechanical ventilation in anaesthesia department
  • Paediatric patients on mechanical ventilation in intensive care department
  • In selected study period between 1.1.2018 - 31.1.2019

排除标准

  • Age outside selected limits
  • Insufficient data

结局指标

主要结局

Tidal volume

时间窗: Intraoperative period

Tidal volume will be evaluated in the paediatric patients in anaesthesia and in intensive care unit

次要结局

  • Driving pressure(Intraoperative period)
  • Positive end-expiratory pressure settings according to the inspiration fraction of oxygen(Intraoperative period)

研究者

发起方
Brno University Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Petr Štourač, MD

assoc.prof.MD,Ph.D

Brno University Hospital

研究点 (1)

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