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Iodine Status in Portuguese Children and the Role of Salt Fortification in School Canteens

Completed
Conditions
Urinary Iodine Status in School Aged Children
Interventions
Other: Iodine status among portuguese school children
Registration Number
NCT02608138
Lead Sponsor
Universidade do Porto
Brief Summary

It is well known that insufficient iodine intakes impairs the production of thyroid hormones, essential for cognitive development and healthy growth.

Although the World Health Organization (WHO) promotes public health measures for an adequate iodine consumption, it is estimated that one in three school age children remain iodine deficient worldwide. Whereas there is no mandatory iodisation programs in Portugal, young infants are among the most vulnerable to iodine deficiency due to their special requirements.

Therefore, the present study aims to evaluate iodine status in school age Portuguese children (6-12y), compare iodine status in children, cognitive outcomes and thyroid health and monitor the use of iodised salt in school canteens exploring potential implications in children's iodine status.

Detailed Description

Iodine is essential for the synthesis of thyroid hormones. Thyroid hormones, especially during periods of increased susceptibility, are crucial for neurodevelopment. Inadequate levels of iodine in the diet may lead to a strong and decisive cognitive impairment which poses a major public health challenge. The World Health Organization prioritized the intake of iodine and recommends the universal enrichment of salt with iodine, so it may reach the general population. In 2013 the Portuguese Department of Education (DGE) issued, as a result of the collaboration with the Portuguese Department of Health (DGS) under the National Program to Promote Healthy Eating a directive introducing the use of iodized salt in school canteens. To ensure the effectiveness and the impact of these policies in Portugal, this project aims to (1) evaluate urinary iodine status in school children (6-12 y), (2) monitor the use of iodized salt in schools, (3) explore potential associations between these parameters. The results of this project will be used to educate food service professionals regarding the use of iodized salt and inform the community about the impact of iodine in health, based on the Norwegian model.

In this study a total of 4800 school aged children will be recruited from approximately 160 schools in the north of Portugal. Parents will be asked to complete the CBCL 6-18, Child Behaviour Checklist and a comprehensive questionnaire which will collect data regarding the child lifestyle and diet. A urine sample will be collected from each participant in school and the Raven's Colored Progressive Matrices will be applied to evaluate children cognitive performance. Anthropometry measurements will be also collected.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
2018
Inclusion Criteria

School children aged 6 to 12 -

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Exclusion Criteria
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
1Iodine status among portuguese school childrenUrinary iodine will be measured at one point in time in school children aged 6-12. A sample of salt used at home and schools will be collected to estimate iodine levels.
Primary Outcome Measures
NameTimeMethod
Urinary IodineOne time point collection
Salt IodineOne time point collection
Secondary Outcome Measures
NameTimeMethod
HeightOne time point collection
Cognitive PerformanceOne time point collection

Raven's Colored Progressive Matrices

Urinary CreatinineOne time point collection
WeightOne time point collection

Trial Locations

Locations (1)

CINTESIS - Faculty of Medicine of the University of Porto

🇵🇹

Porto, Portugal

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