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临床试验/CTRI/2026/03/105361
CTRI/2026/03/105361尚未招募1 期

To compare the analgesic efficacy of local infiltration analgesia (LIA)and pericapsular nerve group to (PENG) block for hip hemiarthroplasty

Dayanand medical college and hospital Ludhiana1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2026年3月16日最近更新:

试验速览

阶段
1 期
状态
尚未招募
发起方
入组人数
80
试验地点
1

研究概览

简要总结

This study aims to compare the analgesic efficacy of Local Infiltration Analgesia (LIA) and Pericapsular Nerve Group (PENG) block in patients undergoing hip hemiarthroplasty. Postoperative pain after hip surgery is significant, and while opioids are effective, they are associated with adverse effects. Therefore, motor-sparing regional techniques like PENG block and LIA are increasingly used to reduce opioid consumption and enhance recovery.

The study will be a randomized, blinded observational trial involving 80 ASA I–III patients aged 18–80 years undergoing hip hemiarthroplasty under spinal anesthesia. Patients will be randomly allocated into two groups:

Group P: Receiving ultrasound-guided PENG block

Group L: Receiving intraoperative local infiltration analgesia (LIA)

All patients will receive standardized spinal anesthesia and postoperative multimodal analgesia. Pain will be assessed using the Visual Analog Scale (VAS).

Primary Outcome:

Total rescue analgesic consumption within 24 hours postoperatively.

Secondary Outcomes:

Time to first rescue analgesic

VAS pain scores

Overall patient satisfaction (5-point Likert scale)

Statistical analysis will compare analgesic consumption and pain scores between groups, with significance set at p < 0.05. The sample size is 80 patients (40 per group), calculated to achieve 95% confidence level and 95% power.

Conclusion:

The study seeks to determine whether PENG block or LIA provides superior postoperative pain control and opioid-sparing effect in hip hemiarthroplasty patients, thereby contributing to improved recovery and patient satisfaction.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • ASA I,II,III electively posted for hip hemiarthroplasty.

排除标准

  • Patient refusal Known allergy to local anaesthetic Contraindication to neuraxial blockade or peripheral nerve blocks Chronic opioid use Infection at site of block Epidural requirement BMI more than 35 kg/m2.

研究者

发起方
Dayanand medical college and hospital Ludhiana
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr M Rupinder Singh

Dayanand medical college and hospital ludhiana

研究点 (1)

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