A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients

Glaxo Wellcome89 个研究点分布在 1 个国家开始时间: 2001年8月31日最近更新: 2005年6月24日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方
试验地点: 89

研究概览研究设计入排标准研究者研究点记录与标识符相似试验

研究概览

简要总结

To determine the safety and efficacy of oral valacyclovir hydrochloride ( 256U87 ) compared to acyclovir in the treatment of recurrent anogenital herpes in HIV-infected patients with CD4 counts = or > 100 cells/mm3.

研究设计

研究类型: Interventional
主要目的: Treatment

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Patients must have:
•HIV infection with CD4 counts = or > 100 cells/mm
•Documented culture of anogenital herpes simplex virus (HSV) within the last 5 years.
•History of recurrent anogenital HSV infection, with a recurrence (with or without culture) within 1 year prior to study.

排除标准

•Co-existing Condition:
•Patients with the following symptoms and conditions are excluded:
•Malabsorption or vomiting that would potentially limit the retention and absorption of oral therapy.
•Concurrent Medication:
•Systemic antiherpes medication.
•Interferon.
•Patients with the following prior conditions are excluded:
•History of hypersensitivity to acyclovir.

研究者

发起方

Glaxo Wellcome

申办方类型

Industry

研究点 (89)

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