Biomarkers of heterogeneity in type 1 diabetes: an integrated approach to clinical and metabolic phenotyping of individuals with established Type 1 diabetes

Completed

Conditions: insulin-dependent diabetes
type 1 diabetes
10018424

Registration Number: NL-OMON47436

Lead Sponsor: Diabeter

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 600

Inclusion Criteria

1. Type 1 diabetes determined by either autoantibodies or based on clinical and historical data, or both
2. At least 5 years of type 1 diabetes
3. Minimum age 16 years
4. Treated for type 1 diabetes at a diabetes center
5. Given informed consent by subject

Exclusion Criteria

1. Non-type 1 diabetes
2. Patients with duration of type 1 diabetes below 5 years
3. Patients under the age of 16 years
4. Pregnancy or breastfeeding, until 3 months (12 weeks) after childbirth or breastfeeding
5. On experimental medication or participating in other studies with conflicting goals and schedules
6. Diseases or conditions that the investigator/physician believes to be a contraindication to participate
7. Unwilling to be informed on incidental findings

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>This biomarker research project intends to gain insight in the heterogeneity of<br /><br>type 1 diabetes en and to gather knowledge on the cause, development and<br /><br>treatment of the disease.</p><br>

Secondary Outcome Measures