Effect of adjunctive locally delivered doxycycline microspheres on clinical parameters and the gingival crevicular fluid matrix metalloproteinase-8 levels in chronic periodontitis

Gingival and dental research center of Tabriz dentistry faculty0 个研究点目标入组 25 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

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•Patients with moderate to severe chronic periodontitis with at least 4 teeth and 4-6mm probe depth were included in the study whose two teeth were at one quadrantand the other two teeth at opposite quadrant of the same patient. The patients shouldn’t have sensitivity to antibiotics of tetracycline group and they also, should not have periodontal treatment till 6 months before. Moreover they shouldn’t take antibiotics 3 months before treatment. Finally they shouldn’t have systemic problem which affects periodontal tissues.
•If the patient had one of following cases, he would be excluded from the study: Having SRP and every periodontal treatment till 6 months before the study, presence of every systemic disorder affecting periodontal position, having allergy history to doxycycline or antibiotics of tetracycline group and taking antibiotics 3 months before the study.

发起方

Gingival and dental research center of Tabriz dentistry faculty