NCT02939508Unknown1 期
Acute Lower Gastrointestinal Dysfunction in Critical Care Patients: Should Colon or Non-colon Originated Lesions be Distinguished?
适应症
试验速览
- 阶段
- 1 期
- 入组人数
- 158
- 试验地点
- 1
- 主要终点
- ICU mortality, n (%)
研究概览
简要总结
This prospective study was designed to compare the difference of effects of conventional treatment, medicine intervention, endoscopic therapy, and surgery between colon originated and non-colon originated ALGID in critical patients, in order to alert doctors to differ the treatment of the two ALGID and provide basis for treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients in our ICU aged 18-75 years.
- •Patients with a confirmed diagnosis of ALGID.
排除标准
- •mechanical intestinal obstruction (including tumor, stercoral obstruction etc.)
- •gastrointestinal hemorrhage within 72 hours.
- •history of inflammatory bowel disease (ulcerative colitis or Crohn's disease) or radiation enteritis.
- •contraindications of neostigmine administration.
结局指标
主要结局
ICU mortality, n (%)
时间窗: 1-28 day after ICU admission
28-day mortality after admission
时间窗: 1-28 day after admission
次要结局
- intra-abdominal pressure(1-28 day after admission)
- Abdominal compartment syndrome(1-28 day after admission)
- ICU stage, (day)(1-60 day after ICU admission)
- Hospitalization, (day)(1-60 day after admission)
研究者
Juanhong Shen
Director, PhD, Principal Investigator, Resident Physician
Chinese Medical Association
研究点 (1)
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