Time-restricted Feeding as a Dietary Strategy Against Metabolic Disturbances in Humans
Not Applicable
Completed
- Conditions
- Overweight and Obesity
- Registration Number
- NCT04351672
- Lead Sponsor
- German Institute of Human Nutrition
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 31
Inclusion Criteria
Inclusion Criteria:<br><br> - BMI 25-35 kg/m²<br><br>Exclusion Criteria:<br><br> - prior diagnosis of type 1 or 2 diabetes<br><br> - weight changes > 5% within past 3 months<br><br> - current shift work or history of shift work<br><br> - traveled across more than one time zone one month before the study<br><br> - poor quality of sleep (PSQI score>10)<br><br> - eating disorders, food intolerance/allergy, severe indigestion<br><br> - Pregnant or breastfeeding<br><br> - severe internal or psychiatric disorders or other conditions that might influence<br> the outcome of the study
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Insulin sensitivity
- Secondary Outcome Measures
Name Time Method Glucose tolerance, fasting glucose, and overall daily glycemic variation;Metabolic hormones and inflammatory markers;Oxidative stress markers;Blood lipids;Blood pressure;Liver enzymes;Anthropometric parameters: body weight;Anthropometric parameters: BMI;Anthropometric parameters: waist circumference;Anthropometric parameters: fat and lean mass;Food intake: eating times;Food intake: calorie intake;Food intake: macronutrient composition;Satiety and hunger scores;Sleep quality and timing;Physical activity;Expression of metabolic genes in adipose tissue;Social and economic decision behaviour