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临床试验/NCT05476692
NCT05476692Unknown不适用

Clinical Outcome of Surgical Treatment for Osteochondral Lesions of the Talus

Assiut University0 个研究点目标入组 40 人开始时间: 2022年10月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
40
主要终点
clinical outcome of the various surgical techniques for treatment of osteochondral lesions of the talus

研究概览

简要总结

Assess clinical and radiological outcome of the various surgical techniques for treatment of osteochondral lesions of the talus

详细描述

Osteochondritis dissecans (OCD) of the talus is a subchondral bone pathology that presents as an osteochondral lesion of the talar dome with consequent articular cartilage abnormalities. Osteochondral lesions of the talus (OLT) are frequent after acute ankle trauma. The natural history of the OLT remains unclear due to paucity of longitudinal follow-up studies. Various treatment strategies have been described for OLT, including conservative treatment and operative treatment However, the current literature does not allow firm evidence-based recommendations concerning the treatment to be established ; Microfracture is the most common reparative surgery for osteochondral lesions of the talus (OLTs). While shown to be effective in short- to midterm outcomes, the fibrocartilage that microfracture produces is both biomechanically and biologically inferior to that of native hyaline cartilage and is susceptible to possible deterioration over time following repair . Arthroscopic debridement (AD) for the osteochondral lesions of the talar dome (OLT) was widely documented in the nineties with satisfactory results. However, in modern treatment algorithms, its role is not described. A frequently used instrument for assessing outcome after ankle and hindfoot injuries is the American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score .

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
15 Years 至 60 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Age from 15 to 60 years old.
  • Traumatic and degenerative etiology.
  • without ankle deformity.
  • No inflammatory arthritis.
  • Absent or corrected ligamentous instability

排除标准

  • Older than 60 years old and younger than 15 years old.
  • Charcot ankle.
  • Vascular injury.

结局指标

主要结局

clinical outcome of the various surgical techniques for treatment of osteochondral lesions of the talus

时间窗: 1 year

clinical outcome of the various surgical techniques for treatment of osteochondral lesions of the talus , Clinical outcome by the AOFAS score ( American Orthopaedic Foot and Ankle Society), the higher score means the better outcome and the lower score means the worse outcome

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mena Magdy Fahmy Dawood

Principal Investigator

Assiut University

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